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CIALIS is the only prescription Erectile Dysfunction (ED) tablet clinically proven to both go to work fast, in as little as 30 minutes for some men, and work up to 36 hours. With CIALIS, you can be ready when the moment is right.

In technical terms Cialis exerts its action by effecting two enzymes, Cyclic guanosine monophosphate (cGMP) and phosphodiesterase type 5 (PDE5) that play important roles in erectile function. Sexual stimulation triggers the local release of nitric oxide (NO) from nerves and endothelial cells in the penis. NO stimulates an enzyme that catalyzes formation of cGMP from the nucleotide guanosine 5-triphospate (GTP) in the penile blood vessels and corpus cavern