Cialis Information UK - Cialis for the treatment of male impotence (ED)

About Cialis and how it helps in Erectile Dysfunction (ED) also known as Male Impotence.

Cialis is a member of a family of drugs called PDE5 Inhibitors. Cialis is now marketed in approximately 40 countries and is available by prescription in pharmacies on five continents.

Cialis was developed by Icos, a relatively small biotech company located in Washington State, in the United States. Icos has formed a 50/50 joint venture with American Pharmaceutical Giant, Eli Lilly & company. The partnership is called Lilly Icos .

How Cialis can help in Male Impotence Cialis UK

To understand how Cialis works, it may be helpful to understand erections.

When a man is aroused, nerve signals are sent from the brain and around the penis. These nerve signals cause chemicals to be released that relax the muscles in the penis. Normally, these muscles are constricted so that blood cannot flow into the penis. When these muscles relax, large amounts of blood are able to enter the penis, causing an erection. An erection is reversed when another chemical (known as phosphodiesterase type 5 [PDE5]) breaks down the chemicals that caused the muscles to relax in the first place. This causes the muscles in the penis to constrict again as blood leaves the penis.

Cialis tablets contain the active ingredient tadalafil, which is a medicine used in the treatment of Erectile Dysfunction (impotence). Tadalafil is called a phosphodiesterase type 5 inhibitor, and works by preventing the action of a chemical in the body called phosphodiesterase type 5.

Cialis UK An erection is produced via a complex chain of events, involving signals from the nervous system and the release of chemical messengers within the tissues of the penis. One of these chemical messengers is called cyclic GMP.

Cyclic GMP causes the blood vessels in the penis to widen by relaxing a thin layer of muscle found in the blood vessel walls. This allows more blood to enter the penis, which ultimately results in the penis becoming rigid and erect.

Cialis works by blocking PDE5. When PDE5 is blocked, more of the chemicals responsible for the erection remain, so the muscles in the penis do not constrict. This allows blood to stay in the penis longer, which allows the man to maintain an erection.

Cyclic GMP is normally broken down by another chemical in the body called phosphodiesterase type 5. Tadalafil works by preventing the action of phosphodiesterase type 5, thus stopping the breakdown of cyclic GMP. This means that the blood vessels are kept dilated for longer, improving blood flow to the penis and maintaining an erection.

As tadalafil enhances the actions of the chemical messengers responsible for producing an erection, it will only work once these messengers are present. This means that sexual stimulation is required for it to produce and maintain an erection. The dose should be taken at least 30 minutes before intended intercourse, and it may produce an erection in response to sexual stimulation for up to 36 hours after taking the dose.

Please note that the erection does not last for 36 hours but the patient can get improved erections within this period of time.

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